{"id":15094,"date":"2018-02-08T16:57:45","date_gmt":"2018-02-08T08:57:45","guid":{"rendered":"https:\/\/tokuhon.blog\/?p=15094"},"modified":"2018-05-12T09:08:08","modified_gmt":"2018-05-12T01:08:08","slug":"%e9%86%ab%e7%99%82%e4%bf%9d%e5%81%a518%ef%bc%9a%e9%82%84%e5%9c%a8%e7%b3%be%e7%b5%90%e8%86%bd%e5%9b%ba%e9%86%87%ef%bc%9f%e8%a6%81%e6%b3%a8%e6%84%8f%e7%9a%84%e6%98%af%e8%bc%89%e8%84%82%e8%9b%8b","status":"publish","type":"post","link":"https:\/\/tokuhon.blog\/?p=15094","title":{"rendered":"\u91ab\u7642\u4fdd\u5065(18)\uff1a\u9084\u5728\u7cfe\u7d50\u81bd\u56fa\u9187\uff1f\u8981\u6ce8\u610f\u7684\u662f\u8f09\u8102\u86cb\u767d\u2502\u5bb9\u8b39"},"content":{"rendered":"<header class=\"Post-Header\"><\/header>\n<div>\n<div class=\"RichText Post-RichText\">\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"15112\" data-permalink=\"https:\/\/tokuhon.blog\/?attachment_id=15112\" data-orig-file=\"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-be12741f5d5ac6b119f5651b723a79fa_1200x500.jpg?fit=1200%2C500&amp;ssl=1\" data-orig-size=\"1200,500\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"v2-be12741f5d5ac6b119f5651b723a79fa_1200x500\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-be12741f5d5ac6b119f5651b723a79fa_1200x500.jpg?fit=1200%2C500&amp;ssl=1\" class=\"aligncenter size-full wp-image-15112\" src=\"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-be12741f5d5ac6b119f5651b723a79fa_1200x500.jpg?resize=756%2C315&#038;ssl=1\" alt=\"\" width=\"756\" height=\"315\" srcset=\"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-be12741f5d5ac6b119f5651b723a79fa_1200x500.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-be12741f5d5ac6b119f5651b723a79fa_1200x500.jpg?resize=576%2C240&amp;ssl=1 576w\" sizes=\"auto, (max-width: 756px) 100vw, 756px\" \/><\/p>\n<p>\u8981\u6e1b\u4f4e\u5fc3\u81df\u75c5\u98a8\u96aa\uff0c\u6211\u5011\u90fd\u77e5\u9053\u8981\u964d\u81bd\u56fa\u9187\u3002\u4f46\u6700\u65b0\u7684\u7814\u7a76\u986f\u793a\u91cd\u9ede\u5176\u5be6\u4e26\u4e0d\u662f\u4f4e\u5bc6\u5ea6\u81bd\u56fa\u9187\uff0c\u771f\u6b63\u9700\u8981\u95dc\u6ce8\u7684\u5f88\u53ef\u80fd\u662f\u8f09\u8102\u86cb\u767dB (apolipoprotein-B)\u3002<\/p>\n<p>\u70ba\u4ec0\u9ebc\u8f09\u8102\u86cb\u767dB\u6bd4\u4f4e\u5bc6\u5ea6\u81bd\u56fa\u9187LDL\u66f4\u91cd\u8981\uff1f\u8f09\u8102\u86cb\u767d\u662f\u4f4e\u5bc6\u5ea6\u81bd\u56fa\u9187\u5176\u4e2d\u7684\u69cb\u6210\u90e8\u5206\uff0c\u82e5\u8f09\u8102\u86cb\u767dB\u8f03\u9ad8\u7684\u8a71\uff0c\u7b49\u65bc\u662f\u81bd\u56fa\u9187\u9ad4\u7a4d\u66f4\u5c0f\u6578\u91cf\u8f03\u591a\uff0c\u9032\u5165\u8840\u7ba1\u5806\u7a4d\u7684\u6a5f\u6703\u4e5f\u8f03\u9ad8\u3002\u6240\u4ee5\u9ad8\u6fc3\u5ea6\u8f09\u8102\u86cb\u767d\uff22\u5c0d\u5fc3\u8840\u7ba1\u5065\u5eb7\u7684\u5371\u5bb3\u8f03\u5927\uff0c<a class=\" wrap external\" href=\"https:\/\/link.zhihu.com\/?target=https%3A\/\/www.ncbi.nlm.nih.gov\/pubmed\/23068583\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" data-za-detail-view-id=\"1043\">\u800c\u7814\u7a76\u4e5f\u986f\u793a\u5728\u4e88\u6e2c\u98a8\u96aa\u65b9\u9762\u8f09\u8102\u86cb\u767dB\u662f\u6bd4LDL\u6e96\u78ba\u7684\u3002<\/a><\/p>\n<figure><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"15111\" data-permalink=\"https:\/\/tokuhon.blog\/?attachment_id=15111\" data-orig-file=\"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-6ec798d4c81d18a8e0ec015da8ed2051_hd.jpg?fit=742%2C433&amp;ssl=1\" data-orig-size=\"742,433\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"v2-6ec798d4c81d18a8e0ec015da8ed2051_hd\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-6ec798d4c81d18a8e0ec015da8ed2051_hd.jpg?fit=742%2C433&amp;ssl=1\" class=\"aligncenter size-full wp-image-15111\" src=\"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-6ec798d4c81d18a8e0ec015da8ed2051_hd.jpg?resize=742%2C433&#038;ssl=1\" alt=\"\" width=\"742\" height=\"433\" srcset=\"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-6ec798d4c81d18a8e0ec015da8ed2051_hd.jpg?w=742&amp;ssl=1 742w, https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-6ec798d4c81d18a8e0ec015da8ed2051_hd.jpg?resize=411%2C240&amp;ssl=1 411w\" sizes=\"auto, (max-width: 742px) 100vw, 742px\" \/><figcaption><\/figcaption><\/figure>\n<p>\u5373\u4f7f\u81bd\u56fa\u9187\u542b\u91cf\u540c\u7b49, \u8f09\u8102\u86cb\u767dB \u8f03\u9ad8\u7b49\u65bc\u662f\u81bd\u56fa\u9187\u9ad4\u7a4d\u66f4\u5c0f\u6578\u91cf\u8f03\u591a\uff0c\u5c0d\u5fc3\u8840\u7ba1\u5065\u5eb7\u7684\u98a8\u96aa\u4e5f\u8f03\u9ad8.<\/p>\n<p>\u5728\u4f5c\u70ba\u6cbb\u7642\u76ee\u6a19\u65b9\u9762\u4e5f\u662f\u8f09\u8102\u86cb\u767dB\u8f03\u70ba\u512a\u52dd\u3002\u8fd1\u5e74\u6709\u4e00\u500b\u53eb\u505aEvacetrapib\u7684\u85e5\u7269\uff0c\u5b83\u662f\u4ee5\u6291\u5236\u81bd\u56fa\u9187\u8102\u8f49\u79fb\u86cb\u767d(cholesteryl ester transfer protein; CETP)\u4f86\u964d\u81bd\u56fa\u9187\u7684\uff0c\u57fa\u672c\u4e0a\u6548\u679c\u5c31\u662f\u963b\u6b62\u9ad8\u5bc6\u5ea6\u81bd\u56fa\u9187HDL\u88ab\u8f49\u5316\u6210LDL\uff0c\u4f46\u5c0d\u8f09\u8102\u86cb\u767dB\u7684\u5f71\u97ff\u5fae\u5c11\u3002\u5728\u81e8\u5e8a\u5be6\u9a57\u4e2dEvacetrapib\u80fd\u589e\u52a0HDL\u8fd1\u4e00\u500d\uff0c\u4e26\u6e1b\u5c11LDL\u903939%\u3002\u9019\u770b\u4e0a\u53bb\u5f88\u6709\u6548\u662f\u4e0d\u662f\uff1f\u4f46\u96a8\u5f8c\u537b\u88ab\u767c\u73fe\u7121\u6cd5\u6e1b\u4f4e\u5fc3\u9ad2\u75c5\u98a8\u96aa\uff0c\u85e5\u7269\u66f4\u843d\u5f97\u4e00\u500b\u7d42\u6b62\u7814\u767c\u7684\u4e0b\u5834\u3002<a class=\" wrap external\" href=\"https:\/\/link.zhihu.com\/?target=https%3A\/\/jamanetwork.com\/journals\/jama\/article-abstract\/2650886%3Fredirect%3Dtrue\" target=\"_blank\" rel=\"nofollow noopener noreferrer\" data-za-detail-view-id=\"1043\">\u6700\u5f8c\u7814\u7a76\u7684\u7d50\u8ad6\u662f\u964d\u81bd\u56fa\u9187\u7684\u6548\u679c\u5176\u5be6\u662f\u4f86\u81ea\u8f09\u8102\u86cb\u767dB\uff0c\u800c\u4e0d\u662f\u6211\u5011\u4e00\u76f4\u8a8d\u70ba\u7684LDL<\/a>\u3002<\/p>\n<p>\u6240\u4ee5\u4e0b\u6b21\u9a57\u8840\u6642\u7559\u610f\u4e00\u4e0b\u8f09\u8102\u86cb\u767dB \u7684\u6fc3\u5ea6, \u53ef\u80fd\u8b93\u4f60\u66f4\u597d\u5730\u4e86\u89e3\u4f60\u7684\u5fc3\u8840\u7ba1\u5065\u5eb7\u3002<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u8981\u6e1b\u4f4e\u5fc3\u81df\u75c5\u98a8\u96aa\uff0c\u6211\u5011\u90fd\u77e5\u9053\u8981\u964d\u81bd\u56fa\u9187\u3002\u4f46\u6700\u65b0\u7684\u7814\u7a76\u986f\u793a\u91cd\u9ede\u5176\u5be6\u4e26\u4e0d\u662f\u4f4e\u5bc6\u5ea6\u81bd\u56fa\u9187\uff0c\u771f\u6b63\u9700\u8981\u95dc\u6ce8\u7684\u5f88\u53ef\u80fd\u662f\u8f09\u8102 [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":15112,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[603689555,603689565],"tags":[603689891,603689667,408829638],"class_list":["post-15094","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical","category-column","tag-603689891","tag-603689667","tag-408829638"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/tokuhon.blog\/wp-content\/uploads\/2018\/05\/v2-be12741f5d5ac6b119f5651b723a79fa_1200x500.jpg?fit=1200%2C500&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9lhKB-3Vs","jetpack_likes_enabled":true,"_links":{"self":[{"href":"https:\/\/tokuhon.blog\/index.php?rest_route=\/wp\/v2\/posts\/15094","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tokuhon.blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tokuhon.blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tokuhon.blog\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/tokuhon.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=15094"}],"version-history":[{"count":1,"href":"https:\/\/tokuhon.blog\/index.php?rest_route=\/wp\/v2\/posts\/15094\/revisions"}],"predecessor-version":[{"id":15128,"href":"https:\/\/tokuhon.blog\/index.php?rest_route=\/wp\/v2\/posts\/15094\/revisions\/15128"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tokuhon.blog\/index.php?rest_route=\/wp\/v2\/media\/15112"}],"wp:attachment":[{"href":"https:\/\/tokuhon.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=15094"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tokuhon.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=15094"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tokuhon.blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=15094"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}